Glossary · Updated 2026-05-22

What Is Epitalon (Epithalon)? The Tetrapeptide Explained

Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) sold for laboratory research use only. Here is what it is and what to check on a COA.

Epitalon, also spelled Epithalon, is a synthetic tetrapeptide composed of four amino acids (alanine, glutamic acid, aspartic acid, and glycine). It was developed from a natural pineal-gland peptide extract called epithalamin and is sold for laboratory research use only.

Origin and research-use status

Epitalon is a synthetic version of a peptide associated with the pineal gland, developed within the Russian peptide bioregulator research programme. Published literature on it is mostly animal and cell work, and this page does not summarise effects or uses.

Why the spelling varies

You will see both Epitalon and Epithalon used for the same compound, along with the related natural extract epithalamin. When comparing vendor products and COAs, confirm the sequence (Ala-Glu-Asp-Gly) rather than relying on the spelling of the name alone.

COA considerations for Epitalon

As a defined four-amino-acid sequence, Epitalon identity is confirmable by mass spectrometry and purity by HPLC. A trustworthy COA names the lab and reports purity with decimals. Watch for products that list the name but do not expose a verifiable per-batch COA.

What to check before buying

Confirm the testing lab is named, the purity figure has decimal precision and matches the label, the batch matches, and a verification key or portal exists where the lab supports one.

Frequently Asked Questions

Is Epitalon the same as Epithalon?

Yes. Epitalon and Epithalon are two spellings of the same synthetic tetrapeptide (Ala-Glu-Asp-Gly). Epithalamin refers to the related natural pineal extract.

How many amino acids is Epitalon?

Four: alanine, glutamic acid, aspartic acid, and glycine. Its short, defined sequence makes mass-spec identity confirmation straightforward on a COA.

Is Epitalon approved for human use?

No. Epitalon is sold as a research compound and is not an approved therapeutic. Nothing here is medical advice.

Related Resources

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